Analysis of Genetic Association Studies
EPI 293
Subject & Catalog Number
Course Information
Description
At the end of this course students will grasp Concept and Theory, Methods and Software Tools needed to critically evaluate and conduct genetic and genomic association studies in unrelated individuals and family samples, including: basic molecular and population genetics, marker selection algorithms, haplotyping, multiple comparisons issues, population stratification, genome-wide association studies, genotype imputation, gene-gene and gene-environment interaction, analysis of microarray data (including gene expression, methylation data analysis, eQTL mapping), next-generation sequencing data analysis and genetics simulation studies. Useful software tools will be introduced and practiced in labs and projects. Students interested in methodology development will find interesting research topics to pursue further. Students interested in application will learn cutting-edge methods and tools for their ongoing projects. Course materials will be updated according to the fast-growing areas of genomics and other omics studies.
Course note: Familiarity with R and UNIX computing environment are highly recommended. Source codes for all lab projects will be provided. Students are encouraged to discuss course prerequisites with the instructor.
Course Prerequisite(s): BST201 and (BST210 or BST213 or EPI204) and (ID200 or EPI200 or EPI201 or EPI505 or EPI500 or ID201); may not be taken concurrently.
Class Notes
THIS CLASS HAS PRIORITY ENROLLMENT
Priority Wave Groups
Wave 1 | SM2 CBQG
Wave 2 | Open Enrollment
Wave 3 | Open Enrollment
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Priority Wave Timing
Wave 1 | 11/13/2025 11:00 AM - 11/23/2025 11:59 PM
Wave 2 | 11/24/2025 12:00 AM - 11/26/2025 11:59 PM
Wave 3 | 11/27/2025 12:00 AM Enrollment Deadline (varies by session)
Any student who does not meet the Wave 1 or Wave 2 criteria can add themselves to the waitlist (if enrollment requirements are met) at any time during the enrollment period. At the beginning of each priority wave, students on the waitlist who meet the Wave’s criteria will be automatically enrolled into any remaining seats in the course (pending no time conflicts)
**Cross-Registrants and Non-Degree Students will be enrolled on a space available basis after the enrollment deadline for the course
Available for Harvard Cross Registration
