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The Chemistry, Biology, and Societal Implications of Genome Editing
CHEM 177

Course Information

Description

The life sciences and medicine are undergoing a revolution stimulated by breakthrough advances in genome editing technologies.  These technologies, including those enabled by CRISPR systems, enable researchers and physicians to modify target DNA sequences in the genomes of living cells, including those in plants, animals, and human patients.  This class will overview the chemistry and biology underlying recent and current genome editing agents.  We will also discuss their current limitations, how they are reshaping medicine and agriculture, and some social and ethical implications of their use.  In addition to attending lectures that present the chemistry and biology of genome editing, students will analyze recent reports from the scientific literature, and will present their analyses and reasoned opinions during the semester.  Participants will also develop and present final projects on an aspect of genome editing to the class at the end of the semester. 

Class Notes

Enrollment is limited and by petition only. For full consideration, submit an enrollment petition by following the directions posted on the course Canvas site.

School Faculty of Arts & Sciences
Credits 4
Cross Reg

Available for Harvard Cross Registration

Course Component Lecture
Subject Chemistry
Grading Basis FAS Letter Graded
Exam/Final Deadline Dec. 11, 2025
General Education N/A
Quantitative Reasoning with Data N/A
Divisional Distribution Science & Engineering & Applied Science
Course Level For Undergraduate and Graduate Students